This study estimates cognitive effort based on functional near-infrared spectroscopy data and performance scores using a hybrid DeepNet model. The estimation of cognitive effort enables educators to modify material to enhance learning effectiveness and student engagement. In this study, we collected oxygenated hemoglobin using functional near-infrared spectroscopy during an educational quiz game. Participants (n=16) responded to 16 questions in a Unity-based educational game, each within a 30-second response time limit. We used DeepNet models to predict the performance score from the oxygenated hemoglobin, and compared traditional machine learning and DeepNet models to determine which approach provides better accuracy in predicting performance scores. The result shows that the proposed CNN-GRU gives better performance with 73% than other models. After the prediction, we used the predicted score and the oxygenated hemoglobin to observe cognitive effort by calculating relative neural efficiency and involvement in our test cases. Our result shows that even with moderate accuracy, the predicted cognitive effort closely follow the actual trends. This findings can be helpful in designing and improving learning environments and provide valuable insights into learning materials.

In recent years, deep learning (DL) approaches have demonstrated promising results in decoding hemodynamic responses captured by functional near-infrared spectroscopy (fNIRS), particularly in the context of brain-computer interface (BCI) applications. This work introduces AbsoluteNet, a novel deep learning architecture designed to classify auditory event-related responses recorded using fNIRS. The proposed network is built upon principles of spatio-temporal convolution and customized activation functions. Our model was compared against several models, namely fNIRSNET, MDNN, DeepConvNet, and ShallowConvNet. The results showed that AbsoluteNet outperforms existing models, reaching 87.0% accuracy, 84.8% sensitivity, and 89.2% specificity in binary classification, surpassing fNIRSNET, the second-best model, by 3.8% in accuracy. These findings underscore the effectiveness of our proposed deep learning model in decoding hemodynamic responses related to auditory processing and highlight the importance of spatio-temporal feature aggregation and customized activation functions to better fit fNIRS dynamics.

People with Multiple Sclerosis (MS) complain of problems with hand dexterity and cognitive fatigue. However, in many cases, impairments are subtle and difficult to detect. Functional near-infrared spectroscopy (fNIRS) is a non-invasive neuroimaging technique that measures brain hemodynamic responses during cognitive or motor tasks. We aimed to detect brain activity biomarkers that could explain subjective reports of cognitive fatigue while completing dexterous tasks and provide targets for future brain stimulation treatments. We recruited 15 people with MS who did not have a hand (Nine Hole Peg Test [NHPT]), mobility, or cognitive impairment, and 12 age- and sex-matched controls. Participants completed two types of hand dexterity tasks with their dominant hand, single task and dual task (NHPT while holding a ball between the fifth finger and hypothenar eminence of the same hand). We analyzed fNIRS data (oxygenated and deoxygenated hemoglobin levels) using a machine learning framework to classify MS patients from controls based on their brain activation patterns in bilateral prefrontal and sensorimotor cortices. The K-Nearest Neighbor classifier achieved an accuracy of 75.0% for single manual dexterity tasks and 66.7% for the more complex dual manual dexterity tasks. Using XAI, we found that the most important brain regions contributing to the machine learning model were the supramarginal/angular gyri and the precentral gyrus (sensory integration and motor regions) of the ipsilateral hemisphere, with suppressed activity and slower neurovascular response in the MS group. During both tasks, deoxygenated hemoglobin levels were better predictors than the conventional measure of oxygenated hemoglobin. This nonconventional method of fNIRS data analysis revealed novel brain activity biomarkers that can help develop personalized brain stimulation targets.

The paper introduces a Fuzzy-based Attention (Fuzzy Attention Layer) mechanism, a novel computational approach to enhance the interpretability and efficacy of neural models in psychological research. The proposed Fuzzy Attention Layer mechanism is integrated as a neural network layer within the Transformer Encoder model to facilitate the analysis of complex psychological phenomena through neural signals, such as those captured by functional Near-Infrared Spectroscopy (fNIRS). By leveraging fuzzy logic, the Fuzzy Attention Layer is capable of learning and identifying interpretable patterns of neural activity. This capability addresses a significant challenge when using Transformer: the lack of transparency in determining which specific brain activities most contribute to particular predictions. Our experimental results demonstrated on fNIRS data from subjects engaged in social interactions involving handholding reveal that the Fuzzy Attention Layer not only learns interpretable patterns of neural activity but also enhances model performance. Additionally, the learned patterns provide deeper insights into the neural correlates of interpersonal touch and emotional exchange. The application of our model shows promising potential in deciphering the subtle complexities of human social behaviors, thereby contributing significantly to the fields of social neuroscience and psychological AI.

Building communication systems that enable seamless and symbiotic communication between humans and AI agents is increasingly important. This research advances the field of human-AI interaction by developing an innovative approach to decode imagined speech using non-invasive high-density functional near-infrared spectroscopy (fNIRS). Notably, this study introduces MindGPT, the first thought-to-LLM (large language model) system in the world. This study focuses on enhancing human-AI communication by utilising fNIRS data to develop a proprietary AI model called MindGPT capable of decoding imagined speech. Hemodynamic responses representing neural activity were collected from four participants instructed to imagine three different sentences.

In the coming decade, artificial intelligence systems will continue to improve and revolutionise every industry and facet of human life. Designing effective, seamless and symbiotic communication paradigms between humans and AI agents is increasingly important. This paper reports a novel method for human-AI interaction by developing a direct brain-AI interface. We discuss a novel AI model, called MindSpeech, which enables open-vocabulary, continuous decoding for imagined speech. This study focuses on enhancing human-AI communication by utilising high-density functional near-infrared spectroscopy (fNIRS) data to develop an AI model capable of decoding imagined speech non-invasively. We discuss a new word cloud paradigm for data collection, improving the quality and variety of imagined sentences generated by participants and covering a broad semantic space. Utilising a prompt tuning-based approach, we employed the Llama2 large language model (LLM) for text generation guided by brain signals. Our results show significant improvements in key metrics, such as BLEU-1 and BERT P scores, for three out of four participants, demonstrating the method's effectiveness. Additionally, we demonstrate that combining data from multiple participants enhances the decoder performance, with statistically significant improvements in BERT scores for two participants. Furthermore, we demonstrated significantly above-chance decoding accuracy for imagined speech versus resting conditions and the identified activated brain regions during imagined speech tasks in our study are consistent with the previous studies on brain regions involved in speech encoding. This study underscores the feasibility of continuous imagined speech decoding. By integrating high-density fNIRS with advanced AI techniques, we highlight the potential for non-invasive, accurate communication systems with AI in the near future.

Functional near-infrared spectroscopy (fNIRS) is employed as a non-invasive method to monitor functional brain activation by capturing changes in the concentrations of oxygenated haemoglobin (HbO) and deoxygenated haemo-globin (HbR). Various machine learning classification techniques have been utilized to distinguish cognitive states. However, conventional machine learning methods, although simpler to implement, undergo a complex pre-processing phase before network training and demonstrate reduced accuracy due to inadequate data preprocessing. Additionally, previous research in cog-nitive load assessment using fNIRS has predominantly focused on differ-sizeentiating between two levels of mental workload. These studies mainly aim to classify low and high levels of cognitive load or distinguish between easy and difficult tasks. To address these limitations associated with conven-tional methods, this paper conducts a comprehensive exploration of the im-pact of Long Short-Term Memory (LSTM) layers on the effectiveness of Convolutional Neural Networks (CNNs) within deep learning models. This is to address the issues related to spatial features overfitting and lack of tem-poral dependencies in CNN in the previous studies. By integrating LSTM layers, the model can capture temporal dependencies in the fNIRS data, al-lowing for a more comprehensive understanding of cognitive states. The primary objective is to assess how incorporating LSTM layers enhances the performance of CNNs. The experimental results presented in this paper demonstrate that the integration of LSTM layers with Convolutional layers results in an increase in the accuracy of deep learning models from 97.40% to 97.92%.

Functional near-infrared spectroscopy (fNIRS) is a non-intrusive way to measure cortical hemodynamic activity. Predicting cognitive workload from fNIRS data has taken on a diffuse set of methods. To be applicable in real-world settings, models are needed, which can perform well across different sessions as well as different subjects. However, most existing works assume that training and testing data come from the same subjects and/or cannot generalize well across never-before-seen subjects. Additional challenges imposed by fNIRS data include the high variations in inter-subject fNIRS data and also in intra-subject data collected across different blocks of sessions. To address these issues, we propose an effective method, referred to as the class-aware-block-aware domain adaptation (CABA-DA) which explicitly minimize intra-session variance by viewing different blocks from the same subject same session as different domains. We minimize the intra-class domain discrepancy and maximize the inter-class domain discrepancy accordingly. In addition, we propose an MLPMixer-based model for cognitive load classification. Experimental results demonstrate the proposed model has better performance compared with three different baseline models on three public-available datasets of cognitive workload. Two of them are collected from n-back tasks and one of them is from finger tapping. From our experiments, we also show the proposed contrastive learning method can also improve baseline models we compared with.

Assessing pain in patients unable to speak (also called non-verbal patients) is extremely complicated and often is done by clinical judgement. However, this method is not reliable since patients vital signs can fluctuate significantly due to other underlying medical conditions. No objective diagnosis test exists to date that can assist medical practitioners in the diagnosis of pain. In this study we propose the use of functional near-infrared spectroscopy (fNIRS) and deep learning for the assessment of human pain. The aim of this study is to explore the use deep learning to automatically learn features from fNIRS raw data to reduce the level of subjectivity and domain knowledge required in the design of hand-crafted features. Four deep learning models were evaluated, multilayer perceptron (MLP), forward and backward long short-term memory net-works (LSTM), and bidirectional LSTM. The results showed that the Bi-LSTM model achieved the highest accuracy (90.6%)and faster than the other three models. These results advance knowledge in pain assessment using neuroimaging as a method of diagnosis and represent a step closer to developing a physiologically based diagnosis of human pain that will benefit vulnerable populations who cannot self-report pain.